Student: Name and Surname
PM4B, Coursework on Advanced Drug delivery systems
This coursework is part of PM4B and it is worth 5% of the PM4B module mark.
Using the knowledge that you have been acquiring as part of the advanced drug delivery lectures in PM4B, and relevant reading, you should propose the design of a new product: a drug delivery/drug targeting system containing one of the drugs below. You should describe the product by filling the table below.
Drug candidates:
Drug
Chemical Structure
Epirubicin
Paclitaxel
Tamoxifen
Name:
Here you should write a name that you are proposing for your technology
Brief description of the technology:
In this section you should draw a diagram of the system that you are proposing and indicate key characteristics of the strategy, including proposed administration route and rationale for using the chosen technology.
Either in this section or in one of the 2 sections below (Methodology and Q.C.) you should also include expected drug content, expected dose etc. If appropriate, you can indicate briefly relevant calculations.
Methodology:
In this section you should describe the methodology that you are suggesting to use to make the proposed system. If appropriate, you should have reaction schemes.
Quality control:
In this section you should list quality control checks that should be carried out on your proposed system and the rationale for doing so.
PK considerations:
In this section you should make some consideration on the expected PK for your technology.
Clinical considerations:
In this section, you should indicate the key factors of your technology that will affect the patient, you can make reference to the parent drug. (for example, is the administration route the same as the parent drug? What side effects would you expect your system to display compared to the parent drug?
Patient population:
In this section you should specify the patient population that you would expect to use this product. [if possible/appropriate, include type of cancer, stage, prior treatments etc.]. You should also indicate the rationale for this choice.
References
5 to 15 references should be included here. You can use Vancouver or Harvard style, but references should be consistent in style.
Overall length 2-4 pages including referencing and figures
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