In adult sickle anemia patients, does the use of morphine in addition to NSAIDS decrease chronic pain compared to NSAIDS alone?
Population: Adult sickle cell Anemia patients (<50yrs) Intervention: The use of morphine in addition to NSAIDS during Chronic pain Comparison: The use of only NSAIDS Outcome: Understand if the addition of morphine decreases chronic pain during sickle cell crisis. Time: One year References Geller, & O’Connor. (2008). The sickle cell crisis: a dilemma in pain relief. Mayo Clinic Proc , 83:320-323. Rees, Williams, & Gladwin. (2010). Sickle-cell disease. . Lancet , 376(9757); 2018-2031